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Mississippi Meatballs

I’m always on the lookout for recipes that deliver maximum taste with minimal effort, and these Mississippi Meatballs really deliver! Made in a slow cooker with real meatballs, this easy recipe is comfort food 101. Grab your Crock Pot and ingredients and get cooking – dinner is served!

A close-up of Mississippi meatballs, coated in a rich, savory sauce and garnished with pepperoncini peppers fresh chopped parsley.

You can’t get much easier than this recipe. I use homemade meatballs because I don’t like the spongy, chemical flavor of processed meatballs, but you can certainly skip making the meatballs and just load your frozen meatballs into the slow cooker.

Once you’ve got the meatballs browned, it all goes into the slow cooker. Set it for a couple of hours, and before you know it, dinner is ready! This dish is meaty, tangy, and makes just the right amount of gravy!

A close-up of a juicy Mississippi meatball on a fork, coated in a flavorful, rich sauce. The background features a plate of meatballs garnished with fresh parsley and accompanied by tangy pepperoncini peppers.

Ingredients

  • Ground beef – I cook with 80/20 ground beef.
  • Breadcrumbs
  • Egg
  • Milk
  • Garlic powder
  • Onion powder
  • Salt
  • Black pepper
  • Au jus gravy mix – Use lower sodium to help control the salt.
  • Ranch seasoning
  • Pepperoncini peppers – You’ll need about 1/2 a cup, or 6-8 peppers. I remove the stems and seeds but you don’t have to.
  • Pepperoncini liquid
  • Water
  • Unsalted butter – Use unsalted butter or your dish could end up quite salty.
An overhead view of labeled ingredients for Mississippi meatballs, including ground beef, an egg, breadcrumbs, milk, butter, pepperoncini peppers, au jus seasoning, ranch seasoning, salt, garlic powder, and onion powder, all arranged on a white marble surface.

How to make Mississippi Meatballs

  1. Combine the ground beef, breadcrumbs, egg, milk, garlic powder, onion powder, salt, and black pepper in a large bowl. Mix until just combined.
  2. Form the mixture into meatballs, about 1 to 1.5 inches in diameter.
  3. Brown the meatballs in a skillet over medium-high heat for about 2-3 minutes per side, then flip them. Layer the browned meatballs into the insert of your slow cooker.
  4. Sprinkle the au jus gravy mix and ranch seasoning over the meatballs.
  5. Add the pepperoncini peppers on top of the meatballs.
  6. Pour the pepperoncini liquid and water into the slow cooker.
  7. Dot the diced butter evenly over the top.
  8. Cover the slow cooker with the lid.
  9. Cook on high for 2-3 hours or on low for 4-5 hours, until the meatballs are cooked through and tender.
  10. Stir gently to coat the meatballs in the sauce before serving.

Step-By-Step Process

Chef Jenn’s Tips

  • For uniform meatballs, use a small ice cream scoop to portion the mixture.
  • If you prefer a milder flavor, reduce the amount of pepperoncini peppers.
  • To prevent the meatballs from sticking, lightly grease your hands before forming them.
  • For a spicier kick, add a few dashes of hot sauce to the mixture.
  • If your sauce looks separated, remove the meatballs and set them aside, then use an immersion blender to blend the sauce and it’ll emulsify the butter into the gravy.

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Make It A Meal

Pair these Mississippi Meatballs with creamy mashed potatoes or buttered egg noodles to soak up the flavorful sauce. A side of steamed green beans or a fresh garden salad complements the richness of the dish, creating a balanced and satisfying meal.

Mississippi meatballs served on a plate with rich gravy, garnished with fresh parsley and a pepperoncini pepper.

Storage

Store any leftover meatballs in an airtight container in the refrigerator for up to 3 days. To reheat, place them in a saucepan over medium heat until warmed through, adding a splash of water or broth if needed. For longer storage, arrange the cooled meatballs on a baking sheet and freeze until solid. Transfer them to a freezer-safe bag or container and freeze for up to 3 months. To reheat, thaw overnight in the refrigerator and warm in a saucepan or microwave until heated through.

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A close-up of Mississippi meatballs, coated in a rich, savory sauce and garnished with pepperoncini peppers fresh chopped parsley.
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Mississippi Meatballs

Mississippi Meatballs are rich, tender, and packed with bold flavors, making them a comforting and satisfying dish. Slow-cooked to perfection with tangy pepperoncini, ranch seasoning, and savory gravy, these meatballs are effortless to prepare and incredibly delicious. Serve them over mashed potatoes, rice, or as an appetizer for a crowd-pleasing dish.
Course Main Course
Cuisine American, Southern-Inspired
Keyword easy meatball recipe, Mississippi meatballs, slow cooker meatballs
Prep Time 10 minutes
Cook Time 4 hours
Total Time 4 hours 10 minutes
Servings 6 servings
Calories 523kcal
Author Chef Jenn

Ingredients

  • 2 pounds ground beef I cook with 80/20 ground beef
  • ½ cup breadcrumbs
  • 1 egg
  • ¼ cup milk
  • 1 teaspoon garlic powder
  • 1 teaspoon onion powder
  • ½ teaspoon salt
  • ½ teaspoon black pepper
  • 1 packet au jus gravy mix
  • 1 packet ranch seasoning 1 ounce packet
  • ½ cup pepperoncini peppers
  • ¼ cup pepperoncini liquid
  • ¼ cup water
  • ¼ cup unsalted butter diced

Instructions

  • Combine the ground beef, breadcrumbs, egg, milk, garlic powder, onion powder, salt, and black pepper in a large bowl. Mix until just combined.
  • Form the mixture into meatballs, about 1 to 1.5 inches in diameter.
  • Brown the meatballs in a skillet over medium high heat for about 2-3 minutes per side, then flip them. Layer the browned meatballs into the insert of your slow cooker.
  • Sprinkle the au jus gravy mix and ranch seasoning over the meatballs.
  • Add the pepperoncini peppers on top of the meatballs.
  • Pour the pepperoncini liquid and water into the slow cooker.
  • Dot the diced butter evenly over the top.
  • Cover the slow cooker with the lid.
  • Cook on high for 2-3 hours or on low for 4-5 hours, until the meatballs are cooked through and tender.
  • Stir gently to coat the meatballs in the sauce before serving.

Notes

Chef Jenn’s Tips

  • For uniform meatballs, use a small ice cream scoop to portion the mixture.
  • If you prefer a milder flavor, reduce the amount of pepperoncini peppers.
  • To prevent the meatballs from sticking, lightly grease your hands before forming them.
  • For a spicier kick, add a few dashes of hot sauce to the mixture.
  • If your sauce looks separated, remove the meatballs and set them aside, then use an immersion blender to blend the sauce and it’ll emulsify the butter into the gravy.

Nutrition

Serving: 5meatballs | Calories: 523kcal | Carbohydrates: 11g | Protein: 29g | Fat: 39g | Saturated Fat: 17g | Polyunsaturated Fat: 1g | Monounsaturated Fat: 16g | Trans Fat: 2g | Cholesterol: 156mg | Sodium: 729mg | Potassium: 491mg | Fiber: 1g | Sugar: 1g | Vitamin A: 328IU | Vitamin C: 9mg | Calcium: 67mg | Iron: 4mg

A Note on Nutritional Information

Nutritional information for this recipe is provided as a courtesy and is calculated based on available online ingredient information. It is only an approximate value. The accuracy of the nutritional information for any recipe on this site cannot be guaranteed.

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